| Customization: | Available |
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| Certification: | QS, CCC, ISO, CE, ISO |
| Shape: | Liquid |
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Tributyrin -- a good source of butyric acid in animals
Butyric acid is the primary source of energy for intestinal cells, but the smell of butyric acid is unpleasant and it is not suitable to be added in large quantities in feed. Tributyrin is an esterification product of 3 molecules of butyric acid and 1 molecule of glycerol.
Tributyrin can be hydrolyzed by endogenous lipase in the small intestine, so tributyrin is a good source of butyric acid for animals.
Tributyrin, as the precursor of butyric acid, is convenient to use, safe, non-toxic and side effects, odorless, and all through the stomach. Tributyrin is to solve the problem that liquid butyric acid is volatile and difficult to add, and to improve the unpleasant smell when using butyric acid directly.
The functional difference of different butyric acid products
| Efficacy | Tributyrin | Sodium butyrate | Coated Sodium Butyrate | Clostridium butyricum |
| Promote intestinal development | √ | √ | √ | × |
| Promote the proliferation and differentiation of intestinal epithelial cells | √ | × | ||
| Direct energy supply | √ | √ | √ | No report |
| Improve immunity | √ | √ | √ | √ |
| Absorption site | Mainly in the small intestine, Partially enters the hindgut* | Complete absorption in the small intestine | Absorbed in the small intestine | Produced only in small amounts in the hindgut |
| Absorption efficiency | Naturally occurring ingredients, High absorption efficiency | Passing the stomach affects efficiency | Coating technology determines efficiency, Uncertain effect | Produced by fermentation, Small amount |
| stability | Stable molecular structure, Pure product without peculiar smell | Easily volatile, strong smell | Weak smell | Butyric acid supply Can not guarantee |
Application in animal nutrition
| Animals | Cycle | Dosage | Results | References |
| Grass carp | 10 weeks | 443.5mg/kg TB | Improved the growth performance and intestinal health of grass carp, enhanced antioxidant and immune capabilities. | Cheng et al. 2021 |
| 48-week-old AA broiler breeder | 8 weeks | 1000mg/kg TB | Improve egg white quality, reduce ovarian apoptosis-related gene expression, and improve reproductive tract function. | Wang et al. 2021 |
| 1 day old Rose 708 broiler | 4 weeks | 0.25%(w/w) | Increased the abundance of bacilli and lactobacilli in chickens infected with Escherichia coli, and increased the diversity of bacterial populations. | Proszkowiec-Weglarz et al. 2020 |
| 24-day-old weaned piglets | 2 weeks | 750mg/kg TB | Increase the average daily gain of weaned piglets, reduce the fecal score, improve the intestinal flora, morphology and barrier function, improve growth performance, and alleviate post-weaning intestinal diseases. | Wang et al. 2019 |
| 1 day old piglet | 3 weeks | TB | Improved growth, intestinal digestion and barrier function of piglets | Dong et al. 2016 |
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